[Hongde Information] The XBB poison baht that "swept the United States" has invaded Shanghai! Will we be able to avoid secondary infections in 2023?
Jan 04,2023
On Christmas Eve, the CDC released its latest map of the new coronavirus strain.
According to the chart, the U.S. epidemic field, BA. 5. BF. Strain 7 has basically retired, BQ. 1.1 and BQ. 1 has reached the peak.
At the same time,XBB one up.
According to data released by CDC12 on March 30, 40.5 percent of new crown cases in the U.S. that week were caused by the highly infectious Omicjon subtype strainXBB. 1.5 strainCaused.
XBB. The proportion of 1.5 strains infected in the week nearly doubled month-on-month.
Scientists say,Due to its extremely high "immune escape" ability, XBB. 1.5 has quickly replaced BQ. 1.1 and BQ. 1, becoming the number one epidemic strain in the United States.
At present, the main epidemic strain in China is BA. 5.2 and BF. 7.
According to the latest news, XBB has been monitored in Shanghai.
Among the 30 major subtypes of Omicjon in Shanghai recently, there is BQ, which is widely popular in Europe and America. 1 family and XBB family.
Of the 25 XBB families monitored this time,There were three cases of XBB. 1.5, fortunately, all cases were imported from abroad and did not cause local transmission.
With a forward-looking perspective, XBB is popular in China, and the probability is only a matter of time.
The resulting panic, from# Montmorillonite powder#Rusking to the hot search is enough to see.
At the beginning of the new year, one"XBB.1.5 strain reached the top in the United States. This strain mainly attacks cardiovascular and cerebrovascular diseases and diarrhea. Everyone should stock up on montmorillonite powder, whole intestine and norfloxacin"Screenshots of the circulating network.
Many pharmacies in Beijing, Shanghai, Chongqing and ShenzhenMontmorillonite powder sold out overnight.
In fact, such blind drug hoarding may be pointless.
Montmorillonite powder is mainly used to treat diarrhea in digestive department. It has astringent effect. Side effect particles are difficult to be discharged from the body and easily cause constipation. In additionMontmorillonite powder alone is not recommended for patients with chronic intestinal disease.
A pharmacy clerk in Chongqing said montmorillonite powder and norfloxacin were sold out.
Norfloxacin, as a kind of broad-spectrum antibiotics, can hinder the role of DNA gyrase of pathogenic bacteria in the human digestive tract and hinder the replication of bacterial DNA, thus inhibiting bacteria.
Commonly used in bacterial diarrhea, such as enteritis, dysentery,It is ineffective against viral diarrhea.
In addition, it should be noted that norfloxacin can hinder the growth and development of bones,Minors under the age of 18 are prohibited from taking norfloxacin.
Although some newly-crowned people do have symptoms of vomiting and diarrhea, which usually relieve themselves within 1 to 3 days, XBB1.5 has not been found to be more likely to violate the cardiovascular and digestive systems.
According to the current research, XBB1.5 is no different from the previous strain, and there is no need to stock up on such drugs.
We still need further scientific understanding of this new mutant strain flowing into our country.
What are the characteristics of the XBB strain?
BQ. 1 and XBB are the two most popular mutant families in Europe and America.
BQ. 1 is Omicjon BA. The sixth generation subbranch produced by 5 mutation, and its daughter line BQ. 1.1 has become a major global epidemic strain.
As two Omicjon BA. The recombinant XBB of the 2 progeny mutant strain has a strong immune escape ability, and it has become the main epidemic strain in Singapore within two weeks.
But XBB is not a new mutant,The strain was first detected in India in August 2022.
Since then, it has spread rapidly. In October, it has been detected in 35 countries and soon became the main epidemic strain in Singapore, Malaysia and other countries.
since then,The XBB mutant strain gradually evolved into the Omicjon subbranch, including XBB. 1 and XBB. 1.5.
The study pointed out that XBB pathogenicity is not significantly enhanced, but because the strain mutation can better bind to human cell receptors,XBB. 1.5 immune escape ability is higher.
XBB. 1.5 immune escape ability and XBB. 1 is quite. The trial showed that in the case of at least two doses of mRNA vaccine, the breakthrough infection BF. 7 is also unable to induce XBB. 1 and XBB. 1.5 high levels of neutralizing antibodies,It is difficult to prevent re-infection.
According to Xu Wenbo, director of the Institute of Viral Diseases of the Chinese Center for Disease Control and Control, at a press conference on December 20, BQ. 1 and XBB, the main performance isIncreased transmission and immune escape.
However, its pathogenicity is not significantly different from that of other variants of the Omicjon series,The rates of severe illness and mortality did not increase significantly in these countries.
"For the time being, there have been no reports of BQ.1 and XBB causing increased severe illness and death in China and abroad."
Will the secondary infection rate increase after XBB becomes an epidemic strain?
Wang Xinyu, deputy director of the Department of Infectious Diseases, Huashan Hospital affiliated to Fudan University, said XBB, BQ. 1. BQ. 1.1 the pathogenicity is similar to the previous strain, the immune escape ability is increased.
As a result, the resulting virus may spread faster than before.
If these strains are encountered, the probability of re-infection depends mainly on two aspects.
On the one hand, the strains encountered again with BA. 5 and BF. 7 How much overlap, if the virus has been mutating, cross-protection is reduced, it may cause infection;
On the other hand, it looks at the person's own antibody levels.
Generally speaking, the antibody level in Yangkang is relatively high for a period of time, and it is not easy to be infected again during this period. But over time, antibody levels drop, leading to the possibility of re-infection.
In general, if there is a certain antibody in the body, the symptoms are relatively lighter and the recovery speed is faster.
In the rare cases where the virus mutates and causes an increase in morbidity, the disease is likely to be worse than the first time.
The evolution trend of the new crown variant strain in the future.
The evolutionary nature of the new coronavirus and global control factors have led to the continuous emergence of new variants of the new coronavirus.
Alfa, Delta, Omicjon and other mutants,The overall trend is that the spread is faster and faster, the immune escape ability is gradually enhanced, and the virulence is getting weaker and weaker,But do not rule out that individual mutations will still lead to the occurrence of severe.
In order to survive, the virus will have an iterative evolution process, but each mutation process is not necessarily a complete iteration.
The direction of future strain changes is not yet certain,The enhancement of transmission and the enhancement of immune escape ability are the general direction of change.
Currently, BQ. 1 and XBB in China has not yet formed a dominant spread,The domestic epidemic is still based on BA. 5.2, BF. 7 mainly, but its spread advantage will gradually increase.
Beijing or Guangzhou epidemic contacts mainly carry BF. 7 and BA. 5.2 substrains,The movement of urban and rural populations during the Spring Festival will greatly affect the direction of the epidemic.
Based on current research, the new coronavirus will not disappear and may eventually evolve into a perennial seasonal flu that may erupt in winter and spring.
In the course of dealing with the new coronavirus, the antibodies present in the human body are gradually metabolized. Strengthening vaccines, good hygiene and a healthy lifestyle are still the long-term preparations we need to make in the face of the new crown.
In addition, scientific psychological construction is also essential.
Hongde International reminds you that whether it is BQ. 1 and XBB, or the current domestic high-spread strains, don't panic hoarding drugs, scientific prevention and control can provide the best protection.

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